Limited evidence suggests that co-morbid chronic physical illness may not increase risk for recurrence in depression

Umbrellas

There is a widespread clinical presumption that people who have both major depressive disorder (MDD) and a co-morbid chronic physical illness represent a ‘double trouble’ group. This leads to the expectation that the depression prognosis for these people would be poor with increasing likelihood of recurrence. Evidence supports the view that depression is prevalent among [read the full story...]

Brain imaging suggests that differences in emotional processing are present before developing depression

Three generations of women

When trying to understand more about about mental health problems one of the big questions is: are the results of a study due to how the person is currently feeling or are the results due to a predisposition to how they are feeling now? While often the answer will be a bit of both, researchers [read the full story...]

SSRIs and TCAs are equally effective at treating chronic depression, but SSRIs have fewer side effects

Tightrope walker

Major depression all too often develops a chronic course, with every episode making future relapse more likely (Gilmer et al., 2005). Dysthymic disorders represent a less severe, but more persistent form of depression lasting for at least two years. In the affective disorder spectrum, chronic forms are unsurprisingly associated with greater functional impairment and overall [read the full story...]

Depression increases risk of all cause mortality (not just heart disease) in diabetes

Depression is associated with mortality of all causes

This blog is coming across the woodland in stereo as the Diabetes and Mental Elf join forces. In 2011 the Diabetes Elf highlighted Depression and Diabetes: a two way street? a systematic review looking at cause and effect of diabetes and depression and the link between diabetes and cardiovascular disease is not contested. However moving forward [read the full story...]

Study shows that adolescents with symptoms of depression and suicidality are more at risk of unhealthy romantic relationships in adulthood

shutterstock_115817539 (1)

Clinical depression is unfortunately relatively common in adolescence with a prevalence of about 5%. The rates of suicide per 100,000 are around 12.0 for females and 14.2 for males aged 15-24 years with suicidality (thoughts or uncompleted attempts at suicide) likely to be higher. Research and clinical experience suggests issues relating to suicide and depression [read the full story...]

Nature vs. nurture: the case of depression. How do your genetic make up and life experiences affect your chances of developing depression?

Collage of human head

One of the first lectures I attended at Medical School was an introduction to the “nature vs. nurture” debate. I recall the general consensus was a bit of both, however it wasn’t until many years later and well into my public health career that I began to see the value of this perspective in improving [read the full story...]

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The case for Chinese herbal medicine in the treatment of depression

Chinese herbs

More people are seeking alternatives to traditional mental health care and as a result, knowledge about the use of complementary therapies by people with mental illness is increasing – particularly for those experiencing anxiety and depression. A recent survey of women with depression revealed that there is a push for more “natural approaches” that match [read the full story...]

Meta-analysis finds insufficient evidence for treatments to improve insight for people with psychosis

Man smiling in sunlight

Research suggests that many people with schizophrenia or related psychoses show a striking lack of insight into their condition (Dam, 2006). Poor insight can have a negative impact on several outcomes, including general adjustment (Stefanopoulou et al., 2009), quality of life (Drake et al., 2007), social functioning (Drake et al., 2007) and rehospitalisation. With this [read the full story...]

CBT is better than nothing for older adults with depression, but so is any form of active support

Old man stretching

Depression is such a widely known issue now that it barely needs introduction. It’s something we Elves have covered with interest, looking at the effectiveness of various treatments, like psychotherapy, medication and exercise. For older adults though, there remains a somewhat hazy picture of what treatments work best. Most of the evidence base for the [read the full story...]

Depression and bipolar disorder linked to an increased risk of developing dementia, says systematic review

Dementia

Dementia and affective disorders (such as depression and bipolar disorder) are usually considered to be completely unrelated afflictions. Yet a number of recent studies have suggested that the risk of developing dementia in later life may be increased for those who have had an affective disorder. A number of systematic reviews have been undertaken to [read the full story...]