Meta-analysis finds medium-sized deficit for IQ-change in schizophrenia patients

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When Kraepelin first described the symptoms of the disorder we now call schizophrenia, he drew particular attention towards the deterioration of cognitive function he observed in his patients and named their condition “dementia praecox”. To this day, cognitive deficits are still regarded as one of the key features of schizophrenia (and related diagnoses), and it [read the full story...]

Joint Crisis Plans to prevent compulsory admissions: a good idea stymied by poor execution?

Doctor and patient talking

Good mental health care should involve the patient in determining their treatment, and should involve the least restrictive form of care possible. Although the Care Programme Approach (CPA) has resulted in patients in England routinely participating in planning their care, compulsory admissions to psychiatric hospitals have continued to rise over the past decade. Involuntary treatment [read the full story...]

Genetic variation is a factor when treating schizophrenia with folate and vitamin B12 supplementation

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Symptoms associated with schizophrenia are often classified into two categories. The classical indicators such as hallucinations, delusions and thought disorder make up the ‘positive’ category whilst apathy and problems with concentration are ‘negative’ symptoms. These negative symptoms have previously been linked to decreased folate levels (Goff et al. 2004) and there is some evidence that [read the full story...]

Community treatment orders fail to reduce psychiatric readmissions for people with psychosis

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Community treatment orders (CTO’s) provide compulsory supervision outside of psychiatric hospital. They require patients to accept clinical monitoring in the community and enable them to be recalled to hospital for assessment if necessary. They do not authorise forcible treatment; however whilst on a CTO a patient may be ordered to meet certain requirements, such as [read the full story...]

Long-acting antipsychotics cost-effective for treatment of schizophrenia, but evidence inconsistent

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Here at Mental Elf HQ we’re expanding our skill set to include economics. Understanding the best way to value health and health care, and improving health outcomes with budget constraints in mind, are the key pastimes of economics elves. We hope to bring you the latest economic evidence in the field of mental health and to [read the full story...]

Meta-analysis finds insufficient evidence for treatments to improve insight for people with psychosis

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Research suggests that many people with schizophrenia or related psychoses show a striking lack of insight into their condition (Dam, 2006). Poor insight can have a negative impact on several outcomes, including general adjustment (Stefanopoulou et al., 2009), quality of life (Drake et al., 2007), social functioning (Drake et al., 2007) and rehospitalisation. With this [read the full story...]

Cochrane review cannot support training to recognise early signs of recurrence in schizophrenia due to low quality evidence

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NICE Guidelines state that around three quarters of people with a diagnosis of schizophrenia experience a chronic illness: with recurrent episodes of remission and relapse.  One way that chronic physical health conditions, such as diabetes and heart disease, are managed is by using early warning signs (EWS) training and this prevention strategy is now often [read the full story...]

Factors stopping the nation from getting back on its feet: a survey of the non-fatal burden of disease due to mental disorder

Helping sister back to her feet

In times of economic adversity, the health and well-being of a nation needs consideration in order to maximise the workforce and productivity. The number of people and the amount of time spent in an adverse health-state is a prominent driver of population ill health.  Most mental illnesses begin early and persist over a lifetime. Approximately [read the full story...]

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Yoga for schizophrenia: meta-analysis shows short-term quality of life improvements

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This blog entry is the second in a series which is examining the mental health benefits of yoga.  Last month I blogged about yoga for psychiatric disorders, and today I shall be looking specifically at the benefits for schizophrenia. The benefits of exercise and physical activity for schizophrenia are increasingly being recognised.  Regular exercise can [read the full story...]

Atypical antipsychotics don’t improve quality of life in treatment-resistant depression

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SSRIs are usually considered first-line treatment against major depression and approximately 50% of patients achieve remission with the drug they try first (Steffens, Krishnan, & Helms, 1997). However, every eighth case proves to be treatment-resistant and does not respond to standard antidepressant treatment at all. As a last resort, second-generation antipsychotics (SGAs) effective in schizophreniform [read the full story...]