Collaborative care for adolescent depression: new RCT shows promise

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Jennifer Laidlaw writes her debut blog on a recent RCT in JAMA about collaborative care for adolescent depression in primary care. The trial concludes that collaborative care is both feasible and effective in improving outcomes, but Jennifer highlights a number of limitations and questions for future research.

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Breastfeeding and postpartum depression

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Clinical Psychologist Sarah McDonald writes her debut blog on a recent cohort study of breastfeeding and postpartum depression, which concludes that the effect of breastfeeding on maternal depression is extremely heterogeneous.

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Cognitive therapy plus antidepressants for depression

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Patrick Kennedy-Williams highlights a new large-scale RCT of combined cognitive therapy plus antidepressants for major depressive disorder. The trial finds that this combination is effective, but only in patients with severe non-chronic depression.

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Antidepressants for depression in pregnancy: new systematic review says the jury’s still out

Nikki Newhouse summarises a recent US health technology assessment of antidepressants for depression in pregnancy and the postpartum period, which concludes that the evidence remains inconclusive about the benefits and harms of antidepressants for depression in pregnancy.

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Cyberbullying and mental health in young people

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Elly O’Brien summarises a recent US survey of adolescents, which investigates the relationship between cyberbullying, mental health and substance use problems, and the moderating role of family dinners.

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Are autism and ADHD associated with antidepressants or maternal depression? The debate continues…

 

Amy Green summarises a retrospective observational study that finds prenatal antidepressant exposure is associated with risk for ADHD, but not autistic spectrum disorders. She considers this complex topic and works out what it all means for pregnant women with depression.

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CBT in primary care is cost-effective for treatment-resistant depression

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Elf economist Chris Sampson reports on the economic evaluation of the CoBalT RCT, which finds that CBT is cost-effective for treatment resistant depression in primary care.

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Exercise for the prevention and treatment of antenatal depression

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Meg Fluharty summarises a recent systematic review looking at exercise for antenatal depression. The review finds preliminary evidence to suggest that exercise may be effective in reducing depression during pregnancy, but the quality of included trials is low to moderate.

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Prenatal SSRI exposure and autism risk: a dilemma for mums-to-be with depression

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Amy Green summarises a population-based study of young children which looks at prenatal exposure to SSRI antidepressants and the social responsiveness symptoms of autism.

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Ketamine for depression: new review highlights the need for an RCT

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Helge Hasselmann reviews a new systematic review of ketamine for depression, which highlights the need for an RCT to provide reliable data on the safety, tolerability and best route of administration.

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