Are there any effective interventions for preventing falls in older people with mental health problems?

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Falls are estimated to cost the NHS more than £2.3 billion per year (College of Optometrists, 2011) and are associated with significant morbidity and mortality. This fact alone should be giving us the drive to look for ways to prevent falls in healthcare settings. A systematic review recently published in BMC Nursing (Bunn et al, 2014) is [read the full story...]

Longer adolescent duration of worry and low mood predicts problems in adulthood: suggests early intervention important

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Adolescent mental health problems are the cause of deep distress to hundreds of thousands of teenagers in the UK. Young Minds estimates that 850,000 children and young people in the UK have a diagnosed mental health problem, and many more may be suffering in silence.  Statistics on how likely it is that an adolescent with [read the full story...]

CBT and motivational interviewing are effective treatments for comorbid alcohol use disorders and depression, says new meta-analysis

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Alcohol use disorder is frequently comorbid with major depressive disorder, and the disease burden associated with this dual diagnosis is considerably greater than that attributed to each disorder in isolation. This creates a problem for clinicians who are trying to treat depressed problem drinkers, because many services are set up to deal with only one [read the full story...]

Ketamine for severe depression: what can we conclude from a small open label study?

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Last week the media reported widely on a study of ketamine for depression (McShane et al, 2014). As usual the headlines made bold assertions, the Telegraph running with “Horse tranquilliser Ketamine could cure severe depression” (Knapton, 2014). But what did the paper authored by an Oxford group and published in the Journal of Psychopharmacology really [read the full story...]

Psychological treatment may be useful in reducing depression and anxiety in people with dementia, says new Cochrane review

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Depression and anxiety are both common conditions in patients with dementia and mild cognitive impairment (MCI), with some studies finding around 30% of patients show at least some depressive symptoms (Enache et al, 2011). Similarly, a study on vascular dementia found around 70% of participants had two or more symptoms of anxiety (Ballard et al, 2000). [read the full story...]

Recent review suggests Agomelatine is as effective as other antidepressants, but controversy persists

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In spite of widely available different antidepressants, major depression does not respond adequately in up to one third of patients. Overall, the need for both reliable and well-tolerated treatment has remained unmet for a sizeable proportion of people with depression. In the past couple of years, there has been controversy about the suitability of Agomelatine (Valdoxan) [read the full story...]

Is the menopause depressing? Not necessarily

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Some of the lady Elves in the forest have been sharing their concerns about the menopause, and whilst keeping an eye out for hot flushes, night sweats and mood swings; what other changes will the menopause will bring?! Well, Freeman and colleagues have some good news and bad news for us. In November 2013, JAMA [read the full story...]

Little differences among antidepressants regarding sexual dysfunction, but bupropion performs best

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Antidepressant treatment is associated with a variety of side effects, including emotional changes, weight gain or fatigue. As pharmaceutical treatment has evolved, clinicians have become increasingly aware of another major adverse effect of modern antidepressants: sexual dysfunction. Current figures estimate that up to every second patient will, at some stage, experience reduced sexual function, which [read the full story...]

Maternal depression may be associated with offspring obesity, according to systematic review

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Maternal depression is a serious mental health condition and does not only affect the mental health of the mother, but also the physical health of her children. One meta-analysis found that up to 19% of women in developed countries experienced an episode of depression in the 3-month prenatal period (Gavin et al., 2005). More specifically, [read the full story...]

Teenagers who have been concussed are three times more likely to have depression, although no one knows why

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Depression in teenagers is a significant problem, with serious and potentially fatal consequences. Estimates of how many teenagers have depression at any one time vary between countries, but overall about 4-5% of mid to late teens worldwide are thought to experience clinical depression every year (Thapar et al, 2012). Much of the current knowledge of [read the full story...]