Just how good are antipsychotics at preventing relapse? Bridging the efficacy-effectiveness gap

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Samei Huda summarises a new network meta-analysis in the Lancet Psychiatry on the efficacy and effectiveness of antipsychotics for schizophrenia in research settings, such as randomised controlled trials, versus real-world and clinical settings.

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Lived experience perspectives of acceptance and commitment therapy for people with psychosis

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Charlotte Huggett reflects on a qualitative study exploring the perspectives of people with psychosis receiving Acceptance and Commitment Therapy following a first episode of psychosis.

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Compassion-focused therapy for psychosis: study suggests it’s feasible and acceptable, so what next?

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Ellen Iredale and Poppy Brown summarise a case-series study on compassion‐focused therapy for distressing hallucinations and delusions in psychosis, suggesting the potential to benefit people with psychosis.

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Early intervention for psychosis: better outcomes in the short term?

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Emanuele Osimo blogs about the 20-year follow up of the OPUS trial, which tested early intervention services for people with first-episode schizophrenia spectrum disorder.

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‘Hearing Voices’ and self-help groups: hope and support for people who hear voices

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Lorna Collins reflects on a systematic review exploring the benefits of Hearing Voices and other self-help groups for people with auditory hallucinations.

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Neuroimaging abnormalities in first-episode psychosis: clinically-relevant or not?

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Joe Pierre considers a systematic review and meta-analysis on the prevalence of neuroimaging abnormalities in first-episode psychosis and the clinical relevance for service users presenting with first-episode psychosis.

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Predicting treatment-resistant psychosis using routine clinical measures

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Lorna Staines summarises a recent study on predicting treatment-resistant psychosis, which suggests that future risk prediction efforts should seek to consider routinely collected data.

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People with psychosis who attend more leisure activities have a higher quality of life

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Lorna Collins reviews a cross-sectional study that found the quality of life of people with psychosis is higher when they participate in leisure activities.

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Trauma informed care on acute inpatient units: reducing self harm and restrictive practices

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Dr Kirsten Lawson is back! In this blog, Kirsten explores a service evaluation of trauma informed care practices in acute inpatient units, looking specifically at reductions in self-harm and restraint practices.

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