Foetal exposure to sodium valproate is linked with autism risk

Pregnant belly painting

The risks of congenital malformations and impact of cognitive development after foetal exposure to anti-epileptic drugs has been known for some time. Sodium valproate is a frequently used drug for epilepsy and other disorders (including bipolar disorder and migraine). The researchers aimed to examine the link between foetal exposure and subsequent development of autism. Methods [read the full story...]

Inappropriate use of antipsychotics to treat behavioural and psychological symptoms of dementia is likely to be more prevalent in care homes and low-income households

Senior man sitting with hand on head

Antipsychotics were discovered as an effective treatment for schizophrenia in the 1950s, but their use was expanded despite lack of supporting evidence, to treat other patient groups.  This included treating aggression, agitation and other behavioural and psychological symptoms of dementia (BPSD). There is evidence that these distressing symptoms can often be prevented or managed without [read the full story...]

The cardiovascular safety of dementia medications: a cross national study

Dice with broken heart

Two of the most widely available medicines for dementia in the UK are cholinesterase inhibitors and a N-methyl-D-aspartate (NMDA) receptor antagonists (NHS, 2013).  Both drugs are popular because they have been found to lead to improvements in dementia symptoms (Raina 2008). However, some have raised concerns about the safety for patients. These concerns are partly [read the full story...]

Short-term recovery from mild cognitive impairment is possible, but an increased risk of further cognitive decline remains

Dementia

The symptoms of mild cognitive impairment (MCI) include problems with cognitive functioning such as day-to-day memory. In some individuals it is the first sign of dementia, whereas in others it may be due to resolvable factors such as being the side-effect of medication (Alzheimer’s Society, 2012). At present it is unclear how many people with [read the full story...]

Do folic acid supplements in pregnancy prevent autism in children? A new cohort study suggests there is a link but more evidence is needed

Pregnant belly

For many mums-to-be it is advised that taking regular folic acid supplements during pregnancy, and whilst trying to conceive, has significant health benefits for their unborn baby, namely around reducing the risk of neural tube defects such as spina bifida (NHS, 2013). However, do these supplements also affect the risk of the unborn baby developing [read the full story...]

Daily psychological demands are associated with progression of carotid artery atherosclerosis

National Heart Month

As the British Heart Foundation National Heart Month draws to a close Lifestyle Elf and I were discussing their blog on heart attacks not being reduced in people taking vitamins and antioxidants which led to us to thinking about the relationship between stress and cardiovascular disease (CVD). Our colleagues in the Pittsburgh Health Heart Project [read the full story...]

People with schizophrenia are significantly more likely to die from heart disease and cancer

Unequal measures

Since starting this blog two years ago, I have written about a number of studies that highlight the health inequalities faced by people with severe mental illness. The evidence keeps piling up and it’s really quite shocking that we are not doing more to diagnose and treat physical health problems in people with conditions such [read the full story...]

SSRI use in pregnancy does not increase the risk of stillbirth, neonatal mortality or post-neonatal mortality

Newborn baby and mother

Studies have shown that the prevalence of depression in pregnant women is 7-19%. Being depressed during pregnancy can result in preterm delivery, which can in turn lead to illness and even death of the newborn child. Researchers have struggled to single out the causes of these risks. Is it the depression, the medical treatment being [read the full story...]

More potassium, calcium and magnesium in the diet, reduces the risk of vascular dementia

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Dementia is a huge issue. As our population ages, the incidence of the disease is on the increase and attempts to prevent and treat the condition with drugs have not been as successful as we hoped. A lot of effort has gone into investigating ways in which lifestyle factors such as diet can impact on [read the full story...]

Risk factors for suicide and accidental death. What can we learn from last episodes of self-harm?

shutterstock_94384915

Self-destructive behaviour is often brought on by mental illness, poverty and other life problems. As individuals spiral down they sometimes come into contact with health and social care services. This may be a primary care visit, emergency treatment in hospital or simple cries for help to friends and family. Hindsight would show us that a [read the full story...]