Antidepressants for depression in pregnancy: new systematic review says the jury’s still out

Nikki Newhouse summarises a recent US health technology assessment of antidepressants for depression in pregnancy and the postpartum period, which concludes that the evidence remains inconclusive about the benefits and harms of antidepressants for depression in pregnancy.

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Second National Audit of Schizophrenia highlights lack of progress for service users and carers

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André Tomlin summarises the second National Audit of Schizophrenia, which highlights that many people with schizophrenia are still not getting the high quality psychological and medical treatment they deserve.

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Eating disorders: mapping the (lack of) evidence

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Helen Bould summarises a recent review that maps the evidence for the prevention and treatment of eating disorders in young people. Her conclusion? A call to arms for more better quality research to help people affected by these serious illnesses.

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Family-based CBT for early childhood OCD: efficient for white, non-minority, upper middle-class children

Obsessive-compulsive disorder has disruptive consequences in young children.

Ioana Cristea reviews a recent RCT of family-based CBT for early childhood OCD and concludes that the results are impressive, but may not be applicable to poorer children from ethnic minorities.

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CBT in primary care is cost-effective for treatment-resistant depression

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Elf economist Chris Sampson reports on the economic evaluation of the CoBalT RCT, which finds that CBT is cost-effective for treatment resistant depression in primary care.

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Mentalization based treatment for borderline personality disorder: a pragmatic trial but with statistical uncertainty

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Andrew Shepherd summarises a matched control study that explores the effectiveness of day hospital Mentalization-Based Treatment for patients with severe Borderline Personality Disorder.

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Interpersonal therapy and imipramine may be effective at reducing suicidal ideation in depression, but more research needed

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Susie Johnson considers how effective conventional depression treatments are at reducing suicidal ideation in depression. The new study she summarises concludes that interpersonal therapy and antidepressants can also reduce suicidal ideation.

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Empowering mental health service users to become more involved in decisions about their care: the DECIDE RCT

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Laurence Palfreyman highlights an RCT of the DECIDE intervention, which aims to build awareness of the service user’s role in decisions about their care including how they can become more involved and seek information from independent sources.

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Face-to-face psychotherapy for chronic pain in children and adolescents: Cochrane review calls for better primary research

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Lisa Burscheidt summarises a recent Cochrane review of psychotherapy for chronic pain in children and adolescents, which concludes that psychological therapies should be considered as a treatment, but better primary studies are needed to help steer pain management decisions.

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