Medication for the maintenance treatment of bipolar disorder

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Elena Marcus summarises a recent network meta-analysis published in The Lancet of the comparative efficacy and tolerability of medication for the maintenance treatment of bipolar disorder.

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The Internet Therapist: adherence to Internet CBT compared to face to face CBT

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Andrés Fonseca appraises a recent meta-analysis of adherence to Internet CBT and face-to-face cognitive behavioural therapy for depression.

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Internet-based CBT for chronic somatic conditions: problematic meta-analysis offers an overly enthusiastic appraisal

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Ioana Cristea critically reviews a recent meta-analysis of Internet-based CBT for patients with chronic somatic conditions. She concludes that the review authors are offering an overly positive interpretation of their results, and that we need more high quality studies before we can recommend online cognitive behaviour therapy for this population.

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Anti-inflammatory drugs for depression: new review points to benefits, but more research needed

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Helge Hasselmann highlights a recent systematic review of anti-inflammatory drugs for depression, which concludes that NSAIDs, in particular celecoxib, decreases depressive symptoms without increased risk of adverse effects. However, the meta-analysis has a number of draw-backs, which make the study findings far from convincing.

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Lifestyle changes for cognition and dementia: better than a new drug?

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Should all molecular research institutes looking at neurodegenerative diseases be replaced by parks, playgrounds and cycle paths? Mark Horowitz highlights a recent systematic review of modifiable risk factors associated with cognition and dementia, which suggests that from a public health perspective, there may be some sense in this idea.

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Short-term psychodynamic psychotherapy for all common mental health disorders?

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For his ninth Mental Elf blog, Mark Smith reports on a Cochrane systematic review of the effectiveness of short term psychodynamic therapies on common mental health disorders.

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Collaborative care for depression: psychological interventions, alone or in combination with medication, offer additional benefits

A recent meta-analysis sought to identify factors associated with improvement in patient outcomes and in the process of care

Ioana Cristea reviews a recent systematic review and meta-analysis of collaborative care for depression, looking to identify factors predicting improvements. The study finds that collaborative care successfully improves both patient outcomes and the process of care for depression.

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Cannabis and mania: what’s the link?

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Kathryn Walsh summarises a systematic review which finds that cannabis use may exacerbate symptoms of mania in those with a diagnosis of bipolar disorder, and trigger symptoms of mania in the general population.

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Long duration of untreated psychosis is associated with a range of poor outcomes

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Joe Judge appraises a recent systematic review and meta-analysis looking at the duration of untreated psychosis as a predictor of long-term outcomes in schizophrenia.

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