Antidepressants for depression in pregnancy: new systematic review says the jury’s still out

Nikki Newhouse summarises a recent US health technology assessment of antidepressants for depression in pregnancy and the postpartum period, which concludes that the evidence remains inconclusive about the benefits and harms of antidepressants for depression in pregnancy.

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Tricyclic antidepressants for ADHD in children and adolescents: Cochrane review finds no evidence to support prescribing

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Helge Hasselman summarises a Cochrane review of tricyclic antidepressants for attention deficit hyperactivity disorder (ADHD) in children and adolescents, which finds low quality evidence and no justification for prescribing these drugs in this group of patients.

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Medication in advanced dementia: how can we judge what is appropriate?

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Caroline Struthers appraises a recent US cross-sectional study of the use of medications of “questionable benefit” in nursing home residents with advanced dementia. She concludes that all medications are of questionable value if they have side effects which might have a negative impact on quality of life or are likely to cause harm.

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Cyberbullying and mental health in young people

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Elly O’Brien summarises a recent US survey of adolescents, which investigates the relationship between cyberbullying, mental health and substance use problems, and the moderating role of family dinners.

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Reducing benzodiazepine prescribing in primary care

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Liz Hughes summarises two recent studies (1 systematic review and 1 RCT) that both investigate brief interventions for reducing the use of benzodiazepines in primary care.

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Second National Audit of Schizophrenia highlights lack of progress for service users and carers

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André Tomlin summarises the second National Audit of Schizophrenia, which highlights that many people with schizophrenia are still not getting the high quality psychological and medical treatment they deserve.

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Lost in anxiety: treatment-resistant anxiety in older people

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Andrés Fonseca appraises a new systematic review of interventions for treatment-resistant anxiety in older people, which finds a disconcerting lack of evidence to help him support the many older patients he sees who are affected by anxiety disorders.

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E-cigarettes and youth: are e-cigs encouraging more use of conventional cigarettes?

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Matt Field reviews the recent cross-sectional survey of e-cigarettes and conventional cigarette use in US adolescents, which found that E-Cig users were more likely to also smoke regular cigarettes than non-users. Does this mean that E-cigarettes encourage the use of conventional cigarettes?

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Are autism and ADHD associated with antidepressants or maternal depression? The debate continues…

 

Amy Green summarises a retrospective observational study that finds prenatal antidepressant exposure is associated with risk for ADHD, but not autistic spectrum disorders. She considers this complex topic and works out what it all means for pregnant women with depression.

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