Bipolar disorder, suicide and criminality

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Elena Marcus summarises a double case-cohort study, which investigates the risk of suicide and criminal behaviours in people with bipolar disorder and their siblings, compared with the general population.

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Collaborative care for adolescent depression: new RCT shows promise

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Jennifer Laidlaw writes her debut blog on a recent RCT in JAMA about collaborative care for adolescent depression in primary care. The trial concludes that collaborative care is both feasible and effective in improving outcomes, but Jennifer highlights a number of limitations and questions for future research.

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CBT versus psychodynamic psychotherapy for social anxiety disorder: long live the dodo or time for a change in research emphasis?

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Andrew Shepherd appraises a study of the long-term outcomes of psychodynamic therapy and cognitive-behavioral therapy in social anxiety disorder, which finds both therapies are efficacious in treating social anxiety disorder in the short- and long-term.

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Breastfeeding and postpartum depression

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Clinical Psychologist Sarah McDonald writes her debut blog on a recent cohort study of breastfeeding and postpartum depression, which concludes that the effect of breastfeeding on maternal depression is extremely heterogeneous.

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Cognitive therapy plus antidepressants for depression

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Patrick Kennedy-Williams highlights a new large-scale RCT of combined cognitive therapy plus antidepressants for major depressive disorder. The trial finds that this combination is effective, but only in patients with severe non-chronic depression.

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One new drug a week: club drugs and novel psychoactive substances

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Meg Fluharty summarises a recent report from the Royal College of Psychiatrists and explores why novel psychoactive substances and club drugs need a different response from UK treatment providers.

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Long duration of untreated psychosis is associated with a range of poor outcomes

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Joe Judge appraises a recent systematic review and meta-analysis looking at the duration of untreated psychosis as a predictor of long-term outcomes in schizophrenia.

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Smoking cessation in the emergency setting

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Olivia Maynard summarises a systematic review of smoking cessation interventions in the emergency setting, which highlights the poor quality and heterogenous nature of the published trials in this field.

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Antidepressants for depression in pregnancy: new systematic review says the jury’s still out

Nikki Newhouse summarises a recent US health technology assessment of antidepressants for depression in pregnancy and the postpartum period, which concludes that the evidence remains inconclusive about the benefits and harms of antidepressants for depression in pregnancy.

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Tricyclic antidepressants for ADHD in children and adolescents: Cochrane review finds no evidence to support prescribing

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Helge Hasselman summarises a Cochrane review of tricyclic antidepressants for attention deficit hyperactivity disorder (ADHD) in children and adolescents, which finds low quality evidence and no justification for prescribing these drugs in this group of patients.

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