CBT in primary care is cost-effective for treatment-resistant depression

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Elf economist Chris Sampson reports on the economic evaluation of the CoBalT RCT, which finds that CBT is cost-effective for treatment resistant depression in primary care.

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Exercise for the prevention and treatment of antenatal depression

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Meg Fluharty summarises a recent systematic review looking at exercise for antenatal depression. The review finds preliminary evidence to suggest that exercise may be effective in reducing depression during pregnancy, but the quality of included trials is low to moderate.

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Helping young people with psychosis return to work: early intervention services need to do more

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Stephen Wood summarises a recent cluster RCT of vocational rehabilitation in early psychosis, which finds that early intervention services need to do more to help young people with psychosis return to work.

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Bipolar disorder and leadership: evidence from a total population study

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Elena Marcus writes her debut blog on a total population study that finds some interesting associations between bipolar disorder and leadership potential, executive roles and political professions.

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Making parity a reality: RCPsych launch manifesto to improve the nation’s mental health

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The Royal College of Psychiatrists have launched a new manifesto today, which calls on the next government to ensure that mental and physical health are given equal value. André Tomlin summarises the key aims and reflects on what has changed in the world of mental health in the 3 years since the Mental Elf was launched.

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Prenatal SSRI exposure and autism risk: a dilemma for mums-to-be with depression

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Amy Green summarises a population-based study of young children which looks at prenatal exposure to SSRI antidepressants and the social responsiveness symptoms of autism.

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Cannabis use in young people linked with lower high school completion and degree attainment

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André Tomlin and Douglas Badenoch voice a note of caution about the Lancet Psychiatry meta-analysis of cannabis use in young people. The study links cannabis use in children with low educational attainment, cannabis dependence, illicit drug use and suicide attempts in later life.

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E-cigarettes: a review of the evidence-base for regulation

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Sally Adams summarises a recent review of e-cigarettes, which looks at use, content, safety, effects on smokers and the potential for harm and benefit.

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Ketamine for depression: new review highlights the need for an RCT

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Helge Hasselmann reviews a new systematic review of ketamine for depression, which highlights the need for an RCT to provide reliable data on the safety, tolerability and best route of administration.

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Placebo for depression: are some sugar pills better than others?

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Joe Judge revels in a new network meta-analysis looking at placebo for depression published in BMC Medicine, which has been supplemented by a series of commentaries and blogs. Thought-provoking stuff!

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